Editorial standards

What we don’t list, and why

Most supplement sites are silent about the things they won’t recommend. We’re explicit. If a product appears in a supplement aisle but doesn’t meet the bar for evidence or safety, it won’t make it into the catalog — and you’ll find it here with the reason.

Marketed as a 'detox' or heavy-metal binder. There is no credible human evidence supporting routine consumption, and supplement-grade zeolite has documented contamination with aluminum and other heavy metals — the very metals it claims to remove.

FDA on heavy metals in supplements

No demonstrated benefit for any condition in human trials. Chronic use causes argyria, a permanent blue-grey skin discoloration. The FDA has issued multiple warning letters to sellers.

NCCIH on colloidal silver

An industrial bleach being sold as a health treatment. The FDA has warned that consumption causes severe vomiting, diarrhea, and life-threatening low blood pressure.

FDA warning on MMS

Contain amygdalin, which releases cyanide on digestion. There are documented cases of acute cyanide poisoning. The 'cancer cure' narrative has been thoroughly debunked.

FDA on Laetrile

An industrial solvent. While it has narrow legitimate medical applications under clinician supervision, it is not appropriate as a consumer supplement.

Animal-organ extracts marketed as 'organ support'. Quality is unregulated, contamination risk is real, and the active doses can mimic prescription hormones without the same oversight.

Marketing claims rely on a fictional category of water structure. No credible mechanism, no supportive evidence.

Outside the scope of an oral-supplement reference. The unregulated injectable market carries serious safety and quality risk; we point users to qualified clinicians instead.

Most products are diluted past the point of containing any active molecule. We don't model placebo as evidence.

NCCIH on homeopathy

Healthy livers and kidneys handle detoxification. Branded cleanse products typically contain a mix of laxatives, diuretics, and herbs marketed under unfalsifiable claims.

These are not supplements. Many are unapproved drugs, illegal in many jurisdictions, and contaminated with undeclared compounds. Outside our scope.

FDA on SARMs

A note

The list grows over time

New products show up every year. If you’ve seen something marketed aggressively that we should evaluate, that’s a useful signal — we’ll add to this list as we go.

Read about our evidence standards →